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See Xenobiotic transporters Antioxidant response, 140 Anuria, 180 Apaf-1 post in apoptosome, 113 repressing by Hsp70, 139 AP endonucleases, part in base excision service, 238 Apoptosis explication and determining, 112 induction via DNA bill, 238 instrinsic pathway, 115 role in alcoholic cardiac myopathy, 279 duty of caspases, 113 Aristolochic acid enzymatic nitroreduction, 250 rвЂњle in Balkans endemic nephropathy, 248 Pungent amines, 306 factual content, 11 Arsenic, 7, 9 presence in tobacco smoke, 298 Arylhydrocarbon receptor (AhR) inducing ligands, 132 structural features, 131 toxicity receptor prototype, 94 Aryl hydrocarbon receptor nuclear translocator (ARNT), 131 Asbestos asbestosis in exposed workers, 254 multifariousness of incarnate forms and individual form, 253 real value, 11 ATF6 activation pathway, 145 function in ER pain response, 145 ATF4, role in ER significance return, 145 Azidothymidine (AZT), hepatotoxic potential, 166 B Groundwork excision patch up (BER), 238 Bcl-2, impersonation in apoptosis, 113 Benzene, bond with leukemia, 74 Benzoquinone, 74 Biliary excretion, importance of mountain, 82 Bioactivation contributions to carcinogen activation, 231 definition and toxicological roles, 95 metabolic activation of NNN and NNK, 304 situation in demon rum toxicity, 265 duty in benzene toxicity, 74 job in chloroform nephrotoxicity, 183 rвЂњle in developmental toxicity, 195 function in paracetamol hepatotoxicity, 164 rвЂњle in the genotoxicity of polycyclic aromatic hydrocarbons (PAH), 301 lines in thioacetamide hepatotoxicity, 172 position in trichloroethylene nephrotoxicity, 184 role in troglitazone hepatotoxicity, 168 impersonation in vinyl chloride toxicity, 248 post of electronic properties, 99 position of macromolecular selectivity, 98 character of metabolite stability, 96 Bisphenol A epigenetic mechanisms in origin abnormalities, 200 production and usage, 214 part in latent toxicity, 50 British Doctors' On, 293 Burley tobacco, 288 Butadiene (BD), presence in tobacco smoke, 308 Butylated hydroxyanisole (BHA), 136 C Cadherins calcium mimicry not later than teratogens, 202 embryonic downregulation next to cadmium, 212 post in developmental toxicity, 201 Index The using software is fling version. 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